News

CCC2 Cause and Effect: Mechanism and Explanation

Events have causes, sometimes simple, sometimes multifaceted. A major activity of science is investigating and explaining causal relationships and the mechanisms by which they are mediated. Such mechanisms can then be tested across given contexts and used to predict and explain events in new contexts.

Cause and effect is often the next step in science, after a discovery of patterns or events that occur together with regularity. A search for the underlying cause of a phenomenon has sparked some of the most compelling and productive scientific investigations. “Any tentative answer, or ‘hypothesis,’ that A causes B requires a model or mechanism for the chain of interactions that connect A and B. For example, the notion that diseases can be transmitted by a person’s touch was initially treated with skepticism by the medical profession for lack of a plausible mechanism. Today infectious diseases are well understood as being transmitted by the passing of microscopic organisms (bacteria or viruses) between an infected person and another. A major activity of science is to uncover such causal connections, often with the hope that understanding the mechanisms will enable predictions and, in the case of infectious diseases, the design of preventive measures, treatments, and cures.” (p. 87)

“In engineering, the goal is to design a system to cause a desired effect, so cause-and-effect relationships are as much a part of engineering as of science. Indeed, the process of design is a good place to help students begin to think in terms of cause and effect, because they must understand the underlying causal relationships in order to devise and explain a design that can achieve a specified objective.” (p.88)

When students perform the practice of “Planning and Carrying Out Investigations,” they often address cause and effect. At early ages, this involves “doing” something to the system of study and then watching to see what happens. At later ages, experiments are set up to test the sensitivity of the parameters involved, and this is accomplished by making a change (cause) to a single component of a system and examining, and often quantifying, the result (effect). Cause and effect is also closely associated with the practice of “Engaging in Argument from Evidence.” In scientific practice, deducing the cause of an effect is often difficult, so multiple hypotheses may coexist. For example, though the occurrence (effect) of historical mass extinctions of organisms, such as the dinosaurs, is well established, the reason or reasons for the extinctions (cause) are still debated, and scientists develop and debate their arguments based on different forms of evidence. When students engage in scientific argumentation, it is often centered about identifying the causes of an effect.

source: http://www.nextgenscience.org/

Recent Articles

  • Observing Beyond our Senses – Overview

    In this module, students focus on the role of physics and engineering in the increasingly interdisciplinary field of systems biology. Centered on a case study requiring instrumentation for field research, the driving question is “How do scientists measure what they cannot directly observe with their senses?”

  • Interested in participating in immunotherapy research?

    Interested in participating in immunotherapy research? Join the melanoma program at UCLA to learn about how we characterize tumor microenvironments in order to advance sequential therapy to combat cancer. You will participate in state-of-the-art immuno-oncology research and will contribute to learning modules so that others can better understand new therapies. This paid internship will provide you with many new wet bench and professional skills! Image from Wang, et al 2021,…

  • Are you interested in helping high schools usher in the future of health?

    Join our Team as an AmeriCorps Member! This 10.5 month position is easy to apply for and can be your first step in making a positive impact by working with high school students, teachers, and STEM professionals to usher in the future of health. Medicine is shifting from a reactive disease-care system to a proactive Systems Medicine discipline that holistically optimizes wellness and minimizes disease. ISB is preparing students for…

  • Science and Math Teachers – need a break from the classroom?

    Consider joining us for a paid summer position! These in-person, summer research and curriculum development positions are easy to apply for and can reinvigorate you for the years ahead. Position Overview Institute for Systems Biology (ISB) is currently hiring teachers to work full-time or part-time for 2 to 7 weeks during the summer of 2022 for anywhere between 80-280 total hours. Since 2004, the Baliga Lab has partnered teachers with…